Dr john Pispidikis. Pispidikis highlights the significance of knowledge the root causes of problems for efficient treatment. Several problems result from dilemmas within the musculoskeletal system, particularly in the neck and spine. Facets such as bad position, muscle pressure, and vertebral imbalance can donate to headache development. These architectural problems can set stress on nerves, ultimately causing the suffering and disquiet generally associated with headaches.